Lorazepam is metabolized in the liver by conjugation into inactive lorazepam-glucuronide. This metabolism does not involve liver oxidation, so is relatively unaffected by reduced liver function. Lorazepam-glucuronide is more water-soluble than its precursor, so gets more widely distributed in the body, leading to a longer half-life than lorazepam.
Lorazepam is broken down (metabolized) in the liver. But unlike many other benzodiazepines, lorazepam metabolism doesn't involve liver proteins
Like oxazepam, it does not require liver oxidation, but only liver glucuronidation into lorazepam-glucuronide. Wyeth's original patent on lorazepam is expired
liver and is known to undergo enterohepatic recirculation. Lorazepam lorazepam (lorazepam injection) under the conditions of actual use. A second
Lorazepam and diazepam are also metabolized, or processed, in the body differently. Lorazepam is metabolized in the liver by a process known as glucuronidation.
Lorazepam is broken down (metabolized) in the liver. But unlike many other benzodiazepines, lorazepam metabolism doesn't involve liver proteins
In the case of benzodiazepines, most are metabolized by the liver. In patients with hepatic disease or liver lorazepam, oxazepam, and
How Long Does Lorazepam Stay In the System? Lorazepam is mainly metabolized in the liver. Once the organ processes the chemicals, it will then
Lorazepam is metabolized in the liver by conjugation into inactive lorazepam-glucuronide. This metabolism does not involve liver oxidation, so is relatively unaffected by reduced liver function. Lorazepam-glucuronide is more water-soluble than its precursor, so gets more widely distributed in the body, leading to a longer half-life than lorazepam.
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