Drugs that cause thrombocytosis

Data Synthesis: Drug-induced thrombocytosis, a form of reactive thrombocytosis cannot be easily differentiated from more common etiologies of reactive thrombocytosis. In all, 43 case reports of drug-induced thrombocytosis from a wide variety of drugs and drug classes were reviewed using a modified Naranjo probability scale that included

The condition arises from a fault in the bone marrow cells leading to over-production of platelets but the cause of the fault is unknown, and this type is not common. [2] When the cause is known such as another disorder or disease, the term thrombocytosis is preferred, as either secondary or reactive thrombocytosis. Reactive thrombocytosis is

Reactive thrombocytosis (RT) Most common cause of thrombocytosis, accounting for 85% of cases. A reaction to another process, such as inflammation, infection, cancer, or iron deficiency. Rarely causes complications even with extremely elevated platelet counts ( 1,000,000/microL). Autonomous thrombocytosis (AT) Accounts for 15% of cases

Drugs. Drug-induced thrombocytosis can result from various causative factors. One proposed mechanism is that certain drugs can cause the release of cytokines, particularly IL6, leading to thrombocytosis. The increased IL6 would then lead to thrombocytosis. Many drugs can induce thrombocytosis, with varying propensities to do so.

Vinca alkaloids have the most convincing data to show that they can induce thrombocytosis through their thrombocyte-stimulating properties. Micona- zole has been implicated in causing thrombocytosis and has a documented case validated by drug re- challenge. Iron, predictably, can cause a transient thrombocytosis.

thrombocytosis in HIV drug users: impact 1. Thrombocytosis and meth. 0 Recommend. Amber Siegel. Posted . Reply Reply

thrombocytosis in HIV drug users: impact 1. Thrombocytosis and meth. 0 Recommend. Amber Siegel. Posted . Reply Reply

Miconazole has been implicated in causing thrombocytosis and has a documented case validated by drug rechallenge. Iron, predictably, can cause a transient thrombocytosis. The beta-lactam antibiotic data are very difficult to interpret due to the possibility of an acute-phase reaction in an infected patient being the cause of the thrombocytosis.

Secondary thrombocytosis, also called reactive thrombocytosis Certain antipsychotic drugs; Certain acne medications; Epinephrine