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by NJ Wesensten 2024 Cited by 390Stimulants may provide short-term performance and alertness enhancement during sleep loss. Caffeine 600 mg, D-amphetamine 20 mg, and modafinil 400 mg were
methylphenidate modafinil Applies to: Concerta (methylphenidate), modafinil. In single-dose pharmacokinetic studies, healthy volunteers given modafinil (200 mg) with dextroamphetamine (10 mg) or methylphenidate (40 mg) exhibited a delay in the absorption of modafinil by approximately 1 hour. The mechanism of interaction is unknown.
However, these studies used relatively high, and thus not completely safe, doses of these drugs (600 mg caffeine and 400 mg modafinil). Therefore, the aim of the present study was to assess the efficacy of a low and medically safe dose of caffeine (200 mg) and modafinil (200 mg) in maintaining cognitive performance during sustained wakefulness.
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by MJ Thorpy 2024 Cited by 141Most patients require the maximum approved dosage (400 mg approved and sometimes up to 600 mg per day for modafinil), but some patients do quite well even on
Modafinil 400 mg attenuated fatigue in a manner comparable to that seen with caffeine 600 mg; these effects were especially salient during the circadian nadir of performance ( through ); modafinil 200 mg also reversed fatigue, but for a shorter duration (3 min) than modafinil 400 mg (8 min) or caffeine 600 mg (6 min). Discussion and
ADDERALL XR. AMPHETAMINE ASPARTATE MONOHYDRATE (1.25 MG)/AMPHETAMINE SULFATE PEMOLINE (75 MG). N06BA07. MODAFINIL. ALERTEC. MODAFINIL (100 MG).
In our previous study, 600 mg modafinil had no effect on state-anxiety but also increased misclassification of emotion as angry, similar as 60 mg MPH (Dolder et al, 2025).
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