Prolia vs alendronate

Boniva (ibandronate), Fosamax (alendronate), and Prolia (denosumab) are effective osteoporosis medications. Boniva and Fosamax are available

Prolia demonstrated superior fracture risk reduction vs alendronate, with a 36% to 50% greater reduction across multiple endpoints 1 Overall fracture relative risk reduction vs alendronate The overall fracture RRR for hospitalized vertebral fracture was 30% (95% CI, 0.40, 1.01), which was not statistically significant

(See Uses of Evenity vs. Prolia below.) Side effects. Certain serious heart-related side effects, Fosamax (alendronate sodium) tablets, for oral use; Fosamax (alendronate sodium) oral

Costs. Prolia and Fosamax are both brand-name drugs. Fosamax is available as a generic medication, alendronate. And there is a biosimilar medication of Prolia available called denosumab.

The benefits of switching to Prolia vs staying on alendronate. In a 1-year study, women who switched from alendronate to Prolia showed a significant increase in bone mineral density (BMD) at the hip and the lumbar spine compared to women who stayed on alendronate, a commonly prescribed bisphosphonate (such as Fosamax ).

Prolia demonstrated noninferiority and superiority (vs alendronate) in total hip BMD 1, increase in BMD vs alendronate The lower limit of the confidence interval excluded the prespecified noninferiority margin (-0.35% for total hip), thus showing the noninferiority of Prolia compared with alendronate

Prolia (denosumab), Zoledronate or Alendronate? To help you decide oseoporosis treatment prolia zoledtonate denosumab alendronate.

Prolia achieved greater reductions in fracture risk in postmenopausal women compared with oral alendronate, according to a real-world study. of fracture vs oral alendronate, with a 36% reduced

Prolia demonstrated noninferiority and superiority (vs alendronate) in total hip BMD1. BMD data results are not meant to imply fracture efficacy and should