Besides inhibiting the synthesis of cholesterol, biosynthesis of coenzyme Q10 is also reduced, since coenzyme Q10 is an intermediate in the mevalonate pathway [7,8]. Statins were shown to reduce serum/plasma levels of coenzyme Q10 by 16 54% and coenzyme Q10 supplementation was reported to increase the levels of coenzyme Q10 in plasma [ 9 ].
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Beta-blocker cardiovascular medications include: Depletions Coenzyme Q10 Taking propranolol or metoprolol may deplete coenzyme Q10.
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