NCT , Usage of Baclofen for Sleep Improvement After Cardiac Surgery. Baclofen (DB )
Baclofen usually helps these patients sleep better but in some patients, it has the opposite effect and makes it hard to get to sleep. This can be minimised by giving the last baclofen dose of the day at around 6pm so it covers the evening but is wearing off by bedtime.
It was reported that baclofen could decrease REM stage sleep especially with high doses, increase stage N3, increase total sleep time, and decrease sleep
baclofen patients reported disturbed sleep. During the high-dose phase baclofen doses averaged 180mg a day and peaked at an average 192mg
Baclofen usually helps these patients sleep better but in some patients, it has the opposite effect and makes it hard to get to sleep. This can be minimised by giving the last baclofen dose of the day at around 6pm so it covers the evening but is wearing off by bedtime.
Baclofen usually helps these patients sleep better but in some patients, it has the opposite effect and makes it hard to get to sleep. This can be minimised by giving the last baclofen dose of the day at around 6pm so it covers the evening but is wearing off by bedtime.
Evidence suggests that baclofen may offer sleep benefits by reducing sleep latency and increasing slow-wave sleep. The use of baclofen has also
baclofen. Cases of central sleep apnoea syndrome have been observed with baclofen at high doses (≥ 100 mg) in patients who are alcohol dependent.
Studies have shown increases in TST, REM sleep, and stages 1 and 2 non-REM sleep after a single dose of oral baclofen (25 mg), as well as a dose
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