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Author: Admin | 2025-04-28
And other hormones with just a few drops of blood. Clomid vs. TRT: what’s the difference?The key difference between Clomid and TRT for low T is how the two medications raise testosterone levels. As we learned earlier, TRT often comes in the form of injections that replace the missing testosterone with pharmaceutically manufactured testosterone. Clomid, a pill taken daily or every other day, uses a different approach to increase testosterone, as it stimulates the body’s own production of testosterone. Here’s what that means: If you have low T, think of your testicles—which are where testosterone is made—as a factory that isn’t able to produce enough testosterone. TRT means you’re skipping your own factory altogether and supplying the product (testosterone) from an outside source. The problem here is that since you’re getting the product from somewhere else, you don’t really need your own factory (testicles) anymore, so it becomes idle and shuts down. With Clomid, however, your factory doesn’t rely on outside products. Clomid relies on your own factory and tricks your brain into making your testicles increase testosterone output. Since TRT can shut down your own testosterone factory (testicles), it comes with a range of side effects. One of them is infertility. Simply put, if the brain notices a high testosterone level because of TRT, it stops telling the testes to produce testosterone and sperm, potentially harming male fertility. Clomiphene, on the other hand, can maintain male fertility while gradually increasing testosterone levels (Wheeler, 2019). That’s why men with low T who want to start a family may opt for clomiphene over TRT.Clomid vs. TRT: which is better?If you’re diagnosed with low T and your healthcare provider recommends treatment, you might wonder what approach is right for you. Should I start injecting testosterone, or shall I ask my healthcare provider about alternatives, like clomiphene? Ultimately, you and your healthcare provider will make that decision together, depending on your medical history and preferences. But one important question you should ask yourself is whether you want to have children anytime soon. As we said earlier, traditional testosterone replacement therapy has the downside of potentially “turning off” the body’s own testosterone and sperm production, which can result in fertility issues (Patel, 2019). So, if you want to be a dad and preserve fertility, ask your healthcare provider if TRT is right for you or if they recommend an alternative, such as Clomid. Another
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