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Author: Admin | 2025-04-28
Receiving digoxin for anorexia, nausea, vomiting, muscle cramps, paresthesia, and confusion. Patients taking digoxin are at ↑ risk of digoxin toxicity because of the potassium-depleting effect of the diuretic. Potassium supplements or potassium-sparing diuretics may be used concurrently to prevent hypokalemia.Assess for tinnitus and hearing loss. Audiometry is recommended for patients receiving prolonged high-dose IV therapy. Hearing loss is most common after rapid or high-dose IV administration in patients with renal impairment or those taking other ototoxic drugs.Assess for allergy to sulfonamides.Assess for skin rash frequently during therapy. Discontinue furosemide at first sign of rash; may be life-threatening. SJS, TEN, or erythema multiforme may develop. Treat symptomatically; may recur once treatment is stopped.Lab Test Considerations: Monitor electrolytes, renal and hepatic function, serum glucose, and uric acid levels before and periodically throughout therapy. Commonly ↓ serum potassium. May ↓ serum sodium, calcium, and magnesium concentrations. May also ↑ BUN, serum glucose, serum creatinine, and uric acid levels.ImplementationDo not confuse Lasix with Wakix.If administering twice daily, give last dose no later than 5 pm to minimize disruption of sleep cycle. IV route is preferred over IM route for parenteral administration.PO May be taken with food or milk to minimize gastric irritation. Tablets may be crushed, if needed. Do not administer discolored solution or tablets.SUBQ The single-use on-body Infusor with prefilled cartridge is preprogrammed to deliver 30 mg over 1st hr followed by 12.5 mg/hr for the subsequent 4 hr. Inspect fluid in prefilled cartridge; solution is clear to slightly yellow; do not
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