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Author: Admin | 2025-04-28
To 12 hours as well. For those that favor convenience and simplicity, taking only one pill of the XR for long-term relief may be preferred.EfficacyAnecdotal reports across the internet will claim that Adderall XR is better than Adderall IR – and vice-versa. This may be somewhat of a placebo effect, but could also be due to absorption differences. Some people may have an easier time absorbing the Adderall IR in tablet format compared to the beads within the capsules of Adderall XR.Assuming your body absorbs one pill better than the other or more smoothly, it could result in a slight difference in terms of efficacy. Delivery of the drug and how it’s processed matters, but just because the IR works better for you, does not mean that it will work better for someone else. That said, since both Adderall IR and XR contain the same ratio of mixed salts, the effect should be nearly identical.FormatsAdderall IR is formatted in an immediate-release tablets. This means that as soon as you take the drug, you’ll get the full effect of the drug within 30 to 60 minutes; many people feel it sooner. Adderall XR is formatted in capsule form containing pellets. Within these capsules, 50% of the pellets are immediate-release, and 50% are delayed-release.This means that when you take Adderall XR, you’ll get the same initial kick within 30 to 60 minutes as you would with the IR version. However, you’ll notice that the drug delivers a “second wind” of effect after the immediate-release pellets are fully processed. This “second wind” is from the other delayed-release pellets that haven’t broken down.By comparison, the immediate-release pellets are comprised of a bead in the center of a drug layer, followed by an overcoating. The delayed-release pellets are comprised of a bead in the center of a drug layer, with an overcoating covered in a release-delaying polymer, covered with a second overcoating. This means that as the first immediate-release pellets are “wearing off” the delayed-release pellets are just kicking in.The combination of immediate and delayed release pellets results in a bimodal distribution of effect that could be achieved by simply taking 2 properly-timed immediate-release tablets. For the sake of convenience, many people like the Adderall XR format. However, if you don’t always need a “second wind” after your first 4 to 6 hours, Adderall IR may be preferred.Medical usesBoth Adderall IR and XR are approved for the treatment of ADHD and narcolepsy. Those with these conditions may prefer to use one format of Adderall over the other, or may use a combination of both. Some individuals with ADHD may have a supply of both Adderall IR and XR to use based on how much cognitively-demanding
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