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Author: Admin | 2025-04-28
For them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.Severe Interactions of ibuprofen include: NoneSerious Interactions of ibuprofen include: apixaban aspirin aspirin rectal aspirin/citric acid/sodium bicarbonate benazepril captopril enalapril fosinopril ketorolac ketorolac intranasal lisinopril methotrexate moexipril pemetrexed perindopril quinapril ramipril tacrolimus trandolaprilIbuprofen has moderate interactions with at least 239 different drugs.Ibuprofen has mild interactions with at least 116 different drugs.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.What Are Warnings and Precautions for Ibuprofen?WarningsCardiovascular riskNonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of serious cardiovascular thrombotic events, myocardial infarction (MI), and stroke, which can be fatal Risk may increase with duration of use Patients with existing cardiovascular disease or risk factors for such disease may be at greater risk NSAIDs are contraindicated for perioperative pain in the setting of coronary artery bypass graft (CABG) surgeryGastrointestinal riskNSAIDs increase the risk of serious GI adverse events, including bleeding, ulceration, and gastric or intestinal perforation, which can be fatal GI adverse events may occur at any time during use and without warning symptoms, Elderly patients are at greater risk for serious GI eventsThis medication contains ibuprofen. Do not take Advil, Motrin, PediaCare Children's Pain Reliever/Fever Reducer IB, or PediaCare Infant's Pain Reliever/Fever Reducer IB if you are allergic to ibuprofen or any ingredients contained in this drug.Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.ContraindicationsAbsolute Aspirin allergy Perioperative pain in the setting of coronary artery bypass graft (CABG) surgery Preterm infants with untreated proven or suspected infection; bleeding with active intracranial hemorrhage or GI bleed; thrombocytopenia, coagulation defects, proven or necrotizing enterocolitis, significant renal impairment, congenital heart disease where patency or the PDA is necessary for pulmonary or systemic blood flowEffects of Drug AbuseNone.Short-Term Effects See "What Are Side Effects Associated with Using Ibuprofen?"Long-Term Effects Long-term opioid use may cause secondary hypogonadism, which may lead to sexual dysfunction, infertility, mood disorders, and osteoporosis. See "What Are Side Effects Associated with Using Ibuprofen?"CautionsUse caution in asthma (bronchial), cardiac disease, congestive heart failure (CHF), hepatic or
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