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Author: Admin | 2025-04-28
Of pigs that includes both T4 and T3. Brand names are Armour Thyroid and NP Thyroid. Limited offer 20% off your first Thyroid Test Oops! Something went wrong while submitting the form. What is levothyroxine?The most commonly prescribed medication for hypothyroidism is levothyroxine, the synthetic T4 drug. Levothyroxine is typically taken orally, and the dosage is adjusted based on the individual’s thyroid hormone levels and response to treatment.Levothyroxine is usually taken once a day, ideally on an empty stomach, and at least 30 minutes to an hour before eating, drinking coffee, or taking calcium or iron supplements. The medication is then absorbed in the small intestine, where it is metabolized and converted into the active form of the hormone triiodothyronine (T3). T3 is the form of the hormone that affects metabolism and other body functions.Levothyroxine is defined as a “narrow therapeutic range drug” because its safe and effective dose range is very small. This means that a slight increase or decrease in dosage can lead to significant changes in the patient’s thyroid hormone levels, resulting in adverse side effects or inadequate treatment.Levothyroxine has a long half-life, which means it takes a long time for the drug to be metabolized and eliminated from the body. It can be challenging to adjust the dosage accurately and prolong the effects of underdosing or overdosing. Therefore, patients taking levothyroxine require close monitoring of their thyroid hormone levels and frequent dosage adjustments to ensure optimal treatment outcomes.Because levothyroxine is a narrow therapeutic range drug, the FDA has established tight potency requirements. Brand name and generic drug manufacturers are expected to maintain a consistent level of potency within a narrow range to ensure efficacy and safety for patients. Specifically, the potency requirements for levothyroxine are set at 95% to 105% of the labeled amount of the
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