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Author: Admin | 2025-04-28
Than a chubby maybe. I have now been on Trimix injections for 3 weeks and am having success. The URO told me the injections bypass the damaged and (hopefully) healing nerves to produce erections and blood flow and that he hopes it jump starts me for later. Last Friday I did take 100mg of Viagra (no injection that night) for the first time since starting injections and I got about a 30% wood. On Sunday night I injected and got about 80% wood (not quite there for penetration yet)and Monday morning I had my first sex dream and woke up with a small erection, which my URO says are all signs that my nerves are starting to wake up.:)Terry the Water GUY Posted 8/24/2011 2:29 PM (GMT -5) The meds did very little for me and half my nerves were spared. Trimix on the other hand worked well.EDIT: I've only heard that the meds work on blood flow and not nerves. PostopRegular Member Joined : Feb 2010 Posts : 386 Posted 8/24/2011 8:08 PM (GMT -5) How do these meds work? Erections result from parasympathetic nerves that go to blood vessels in the penis. The nerves release nitrous oxide to cause an erection. The nitrous oxide acts on receptors in the smooth muscle on the walls of blood vessels, and cause them to make a substance called cGMP. The cGMP makes the blood vessels dilate and fill with blood. There is an enzyme called cGMP-specific phosphodiesterase type 5, which breaks down the cGMP, getting rid of it so the blood vessels are no longer engorged with blood. Drugs like Viagra, Levitra and Cialis block the enzyme (cGMP-specific phosphodiesterase type 5) which allows more cGMP to build up in the wall of the blood vessel to enhance the effects of nerve activation.So, no nerve, no nitrous oxide, no cGMP being made, so Viagra has no effect. Poorly functioning nerve, some nitrous oxide released, some cGMP made, Viagra allows more cGMP to accumulate: poor erection becomes a better one.Why can Viagra make you see blue? It has some action on a different kind of phosphodiasterase enzyme that's in the retina. 142Veteran Member Joined : Jan 2010 Posts : 7298 Posted 8/24/2011 8:28 PM (GMT -5) Explanations so far are correct in various parts. The last part is (per Scardino & Mulhal's books) the effect of relaxing the smooth muscle tissue, allowing more blood flow. So now we have an effect that allows more blood to flow, and one which lessens the effect of the natural component (PDE-5) that limits the length of an erection.
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